PLAUR and Lyme disease: To elucidate the roleand function of uPAR in the development of Lyme borreliosis in vivo we infectedwildtype (WT) and uPAR knock-out C57BL/6 mice with B. burgdorferisensu stricto and monitored B. burgdorferi numbers in multipleorgans, histopathological changes of tibiotarsi and heart, and host immuneresponses.