FLT1 and cancer: Important cancer related genes identified for this phenotype are CDK6 gene, which inhibits proliferation of human mammary epithelial cells (Lucas et al. 2004); SIAT4C, which is down-regulated in RCC (Saito et al. 2002), RHOB, which is known to be a pro-apoptotic and tumor suppressor gene, and the FLT1 and TFF3 gene.