CXCL12 and small cell lung carcinoma: Previously, we have shown that immobilised CXCL12 induces VLA-4-mediated adhesion of SCLC cell lines to immobilised VCAM-1 and fibronectin, which could be inhibited by pertussis toxin and rho-kinase inhibitors (Burger et al, 2003; Hartmann et al, 2005).