Generally, the expression of cytokeratins (AE1-AE3, Cam5.2, CK7, and EMA) and melanocytic markers (HMB45 and melan A) were rare and weak, the expression of vimentin was variable and weak, and that of E-cadherin, α-methylacyl-coenzyme A racemase, CD10 and RCC were common and strong in Xp11.2 translocation RCCs [5,14,17,19]. This evidence concerns the gene PMEL and renal cell carcinoma.