In order to determine if the BCL3 (19q13.3) gene located on the chromosome 19 was involved in the novel translocation observed by the classical cytogentic analysis above [t(X;19)(p11.2;q13.1)], cultured and uncultured tumor cells were evaluated by interphase FISH analysis using a dual-color break-apart DNA probe within the BCL3 gene on 19q13.3. The gene discussed is BCL3; the disease is neoplasm.