The involvement of some of the genes affecting cancer cell death–Adm, Cflar, Cyr61, Ddit4, Itgb1, Mapk1, Mapk8, Tgfβ2, Tpm1, Vegfα and Wasf1, was demonstrated in breast cancer cell lines [see Additional file 1, data sheet C]. The gene discussed is DDIT4; the disease is breast carcinoma.