However, in the female subgroup (433 cases, 243 controls) the SNPs rs7574865STAT4, rs2476601PTPN22, and rs10499194OLIG3/TNFAIP3 were associated with susceptibility to RA [see Table S4 in Additional data file 1], even after correction for multiple testing (Pcorr = 2.8 × 10-5, Pcorr = 9.0 × 10-3 and Pcorr = 0.037, respectively). This evidence concerns the gene TNFAIP3 and rheumatoid arthritis.