This is in accordance with the study by Yasuda and colleagues, who reported that an increase in the serum concentration of soluble TREM-1, in samples taken within the first 72 hours after the onset of AP, correlated with Ranson score and Acute Physiology and Chronic Health Evaluation (APACHE) II score, and that soluble TREM-1 concentration was higher in patients with early organ dysfunction [30], who have a higher risk of death. Here, TREM1 is linked to alkaline phosphatase measurement.