GSTM1 and G6PD deficiency: Several of those diseases and xenobiotics have already been shown to favorably influence the course of malaria, including sickle-cell trait, beta-thalassaemia-trait, homozygous Hb-C and G6PD-deficiency [7,26-30], iron deficiency [1], lead [2], chlorpromazine [31] and cyclosporine [32].