Moreover, eryptosis is enhanced in a variety of clinical conditions including iron deficiency [23], sickle-cell anaemia [65,66], beta-thalassaemia [7], glucose-6-phosphate dehydrogenase (G6PD)-deficiency [7], phosphate depletion [67], Haemolytic Uremic Syndrome [68], sepsis [69], malaria [25] and Wilson disease [64]. This evidence concerns the gene G6PD and hyperinsulinemic hypoglycemia, familial, 4.