For posterior RG-2 gliomas there was a significant percent change in Gd-DTPA AUC with bradykinin B2 receptor agonist infusion (F4,35 = 6.72, p = 0.0004), but no statistically significant tumor volume effect (F1,35 = 3.01, p = 0.0915). This evidence concerns the gene BDKRB2 and glioma.