Similarly, augmented proportions of TP+ cells, CD3+P+ cells and CD4+P+ cells (Figures 3(a) and 4(a)) were found in patients elected for OC, which preoperatively, had higher preoperative levels of CRP, AP, B, AST and ALT (Figure 1), suggesting that preoperative inflammation and cholestasis affected the perforin-related events. This evidence concerns the gene PRF1 and cholestasis.