Beside its expression on colon cancer cells, CXCR3 is indeed expressed on T lymphocytes, dendritic cells, monocytes, natural killer cells (Qin et al, 1998; Katschke et al, 2001; Penna et al, 2002; Rabin et al, 2003) and was reported as an important receptor for the immune response to be optimally executed (Loetscher et al, 1996). Here, CXCR3 is linked to colonic neoplasm.