CRP and neoplasm: Furthermore, in our study, the tendency of +1059 C-allele carriers to have metastases more often and to be younger at the time of diagnosis when compared to GG homozygotes (P=0.06 for both; Supplementary Table 5) points to a function for CRP haplotype/genotype in actual tumour growth and disease progression, but this result was also not significant after Bonferroni correction.