When the AG and GG groups were combined, the AA genotype was significantly correlated with a higher KDR mRNA level in tumor tissues (mean, 4.32 ± 0.40), compared with the AG/GG genotype (mean, 4.06 ± 0.50, t = 2.178, P = 0.032, independent sample t-test, two-tailed; Table 2). This evidence concerns the gene KDR and neoplasm.