SDHD and paraganglioma: 1, 2 and 3). This correlates well with the observation that sporadic as well as SDHD -linked and PGL2 linked paragangliomas of the head and neck share important clinical characteristics like the age of onset of symptoms, the indolent growth pattern, and a usually benign behaviour of the tumor, although multiple paragangliomas are less often observed in sporadic cases [31-34]. Furthermore, all head and neck paraganglioma subtypes share the typical histological architecture of the 'zellballen', groups of neoplastic chief cells surrounded by sustentacular cells[35,36].