INS and Hyperglycemia: In essence, higher levels of DHA (which can be generated by higher levels of dietary or transfused ascorbate or DHA itself), will compete with glucose for the GLUT transport sites; DHA competition for glucose binding sites on insulin-like regions of GLUT may decrease auto-glycation of GLUT (as well as on insulin and the insulin receptor), thereby helping to prevent some of the deleterious effects of hyperglycemia.