TP53 and head and neck squamous cell carcinoma: Our study provides for the first time evidence that individuals carrying both p53 exon 4 and p53 intron 6 variant allels are significantly protected against SCCHN, while an additional risk is conferred by the combination of p73 exon 2 G4C14-to-A4T14 and p53 intron 3 variant alleles.