In a study by Chan et al. [122] “serrated” polyps were analysed for mutations in BRAF or k-ras. They found of these serrated polyps, BRAF mutations were found in 36% of hyperplastic polyps(HP), 20% of admixed hyperplastic polyp/adenomas(HP/AD) and 100% of serrated adenomas (SA). This evidence concerns the gene KRAS and Alzheimer disease.