It was initially thought that an ABC-protein drug pump for CQ must therefore exist in drug-resistant P. falciparum, similar to the drug pump proposed for tumor cells (human multidrug resistance protein 1 [HsMDR1], also known as Pgp) believed by many investigators to directly translocate vinblastine and many other anti-tumor drugs. The gene discussed is ABCB10; the disease is neoplasm.