Other genes involved in gastric carcinogenesis, disease progression and survival are hypoxia-inducible factor-1α (Hif-1α) [11], the novel gene urg4 [79], r-ras [80] fhl2 [81], and the ribosomal protein L15, which has been associated with cell proliferation in GC, outlining its potential as a therapeutic target [82]. Here, RRAS is linked to gastric cancer.