Fourteen genes (CD3E, DUSP1, IFIT2, LTBR, PIR, FOS, CD14, CEBPB, TIMP3, ICAM3, MAPK14, SEPP1, NFIL3, and SLC40A1) had profiles of expression that generally decreased over time in PBMC from one or both breeds after infection (Fig. 5). The gene discussed is ICAM3; the disease is infection.