MIR30B and cancer: MIRs regulating the expression of AM genes (most frequently endowed with anti-apoptotic functions) also are localized in regions frequently altered in cancer: MIR9-1, MIR29B2, MIR29C, MIR181B1, MIR199A2, MIR205, MIR213 map to chromosome 1 long arm, a gain-prone region in 6 out of 14 of cancer models; the same is true for MIR30B and MIR30D, both localized at 8q24.22, a gain-region in 7/14 of cancer models (Figure 5, Panel B).