CHEK1 and carcinoma: These results are in agreement with previous studies where diallyl trisulfide, resveratrol and lithium caused G2/M cell cycle arrest by activation of Chk1 in human prostate (Herman-Antosiewicz and Singh, 2005), ovarian (Tyagi et al, 2005) and hepatocellular (Wang et al, 2008a, 2008b) carcinoma cells.