To determine the role of CXCR1 or CXCR2 in melanoma tumour growth, SBC2-transfected (SBC-2-CXCR1, SBC2-CXCR2 or SBC-2-control) and A375P-transfected (A375P-CXCR1, A375P-CXCR2 or A375P-control) cells were injected subcutaneously in nude mice and monitored for tumour growth. The gene discussed is CXCR2; the disease is neoplasm.