One of these has been shown to be overexpressed in PCa-PCA-3 (de Kok et al, 2002) and the other is a product of a chromosomal rearrangement, which creates a common prostate cancer-specific product, the TMPRSS2:ERG fusion (Tomlins et al, 2005). The gene discussed is TMPRSS2; the disease is prostate carcinoma.