Indeed, the FC of the genes encoding CXCL10, IL-24, IFNγR2, TLR2, S100A8 and S100A9 were significantly (P<0.05) higher in cftr-transfected CF-TG cells than in CF-TG cells, and were near of those of the genes expressed by wt TG cells stimulated with P. aeruginosa products (Figure 6). Here, S100A8 is linked to cystic fibrosis.