WT1 and neoplasm: In further bioinformatics analysis searching for the transcription factor binding sites with the TFSEARCH program http://mbs.cbrc.jp/research/db/TFSEARCH.html, we found that the 626G allele, but not the 626A allele, creates a new binding site of SRY that is a functional target of the tumor suppression gene WT1 [52], and that the 626G allele in LD with Glu185 may function in prohibiting carcinogenesis.