The latter gene, GPR143, causes ocular albinism type 1 (OA1), which is an X-linked albinism that mainly effects pigment production in the eye in which affected males show all the ocular signs of albinism including severely impaired visual activity, nystagmus, photophobia, iris transillumination, hypopigmentation of retinal pigmented epithelium, foveal hypoplasia, and misrouting of optic tracts [7]. This evidence concerns the gene GPR143 and X-linked recessive ocular albinism.