Using logistic regression analysis, in the multivariate model, adjusted for all baseline parameters, we found that only the advance histological stage of liver disease (P = .015) and the presence of genotype-1 HCV infection (P = .003) were independent predictors of non-SVR, whereas BMI (P = .451), anti-HBc seropositivity (P = .726) as well as patients age (P = .055) were not (Table 3), even taking into consideration the age subgroups (<35 years; P = .151, 35–55 years; P = .441, >55 years; P = .058). This evidence concerns the gene KRT88P and liver disorder.