Moreover, obesity and cardiac lipid accumulation has been associated with increased heart expression of genes that stimulate local production (i.e. lipoprotein lipase (LPL)) and transport protein mediated uptake (i.e., fatty acid translocase (FAT/CD36), fatty acid transporter protein 1 (FATP1) and fatty acid transporter protein 4 (FATP4)) of free fatty acids [5]. The gene discussed is SLC27A4; the disease is obesity due to melanocortin 4 receptor deficiency.