The present study describes the expression of several iron-related genes including hepcidin (HAMP), HFE, neogenin(NEO1), transferrin receptor 1 (TFRC), transferrin receptor 2 (TFR2), and hemojuvelin(HFE2) in normal human brain, brain tumors, and astrocytoma cell lines. Here, HFE is linked to astrocytoma (excluding glioblastoma).