Louse infection grade showed highly significant negative association with TLR2 responses to HKLM (LMM, F1,81.1 = 18.90; P < 0.001) and zymosan (LMM, F1,75.0 = 9.54; P = 0.003), TLR9 response (LMM, F1,80.6 = 7.20; P = 0.009) (Figure 6B–D) and TIR (LMM, F1,80.7 = 17.03; P < 0.001). The gene discussed is TLR9; the disease is infection.