INS and fetal growth restriction: In a cohort of newborns in whom fetal growth velocity had been recorded in a prospective and standardized manner and using the customized percentiles, a method that allows a precise evaluation of fetal growth restriction by identifying newborns who have failed to reach their genetic potential of growth [19], we have recently reported that fetal growth restriction by itself, independently from birth weight, is able to induce changes in body composition with a lower fat mass and changes in metabolism with a higher insulin sensitivity [20].