Specific genes include Il6, Cd74, CaII, Bcl2l2, Cxcl13, and Ccr7. Thus, given the extent of the overlaps already seen, C57BL/6.NOD-Aec1Aec2 mice appear to offer a unique opportunity to identify genetic factors regulating processes leading to SjS. This evidence concerns the gene CCR7 and Schwartz-Jampel syndrome.