PON1 and breast cancer: Therefore, since these genes are all related to the control of oxidative stress-inducing mechanisms, we would like to emphasize that the detection of the GSTP1IleVal-PON1/192QR-PON1/55LM-GLO1AE or GSTP1IleIle-PON1/192QQ-PON1/55MM-GLO1EE genotype combination at individual level, might lead to the identification of patients with intermediate and high risk for BC, respectively (Table 11), compared to the GSTP1ValVal-PON1/192RR-PON1/55LL-GLO1AA genotype combination.