McClung et al(81) have shown by cDNA array analysis that secreted protein acidic and rich in cysteine, which is highly expressed in human gliomas and promotes glioma invasion, upregulates membrane type 1‐matrix MMP and matrix MMP‐2 transcripts, coincident with both increases in secreted galectin‐3 and the proteolytically processed form of galectin‐3. This evidence concerns the gene MMP2 and glioma.