In Hs683 glioma cells a decrease in galectin‐1 expression does not induce apoptotic or autophagic features and does not induce LMP, but is found to modulate p53 transcriptional activity and decrease p53‐targeted gene expression including DDIT3/GADD153/CHOP, DUSP5, ATF3 and GADD45A (64). Here, DDIT3 is linked to central nervous system cancer.