AURKA and neoplasm: Thus, 343 isolates showed activity against the tumor cell line (16.8%), 101 against C. albicans ATCC 10231(4.9%), 198 against S. aureus ATCC 51650 (9.7%), 59 against PTP1B (2.9%); but only 3 and 9 strains were active against caspase 3, and aurora kinase A, respectively.