Lastly we found a significant association between endotoxin levels and insulin (R2 = 0.032; p < 0.001, figure 3a) and glucose (R2 = 0.076; p < 0.001, figure 3b) in the type 2 diabetics, which was not present in the ND group (figure 3c and 3d). Here, INS is linked to type 2 diabetes mellitus.