We carried out IHC for eIF4E, 4E-BP1, 4E-BP2 and p4E-BP1 on TMA sections and assessed immunoreactivity within tumour cells, taking into account the proportions of cells staining positively and average intensity, giving scores of 0 (negative) or 2–7 (positive). Here, EIF4EBP2 is linked to neoplasm.