CDKN2A/B deletion was also observed in Res259 astrocytoma cells, which also contained the well-described 4q12 amplicon, resulting in high level gains of the oncogenes PDGFRA and KIT, and low-level gain of a region including KDR/VEGFR2. Here, CDKN2A is linked to astrocytoma (excluding glioblastoma).