Our data differ from those obtained in experimental infections with C. trachomatis or C. muridarum genital tract infection, where Nod1 deficiency had no significant effect on the efficiency of infection, or pathology in vaginally infected mice, while Rip2-deficient mice had only slightly increased bacterial load and delayed bacterial clearance and mildly increased oviduct inflammation [56]. This evidence concerns the gene RIPK2 and infection.