Levels of plasma circulatory markers viz IL-4, IL-8, IL-13, ICAM-1and VCAM-1 were significantly higher (P < .001, <.001, .004, <.001, <.001) in contrast to, levels of IL-10 and IFN-λ which were significantly lower (P < .001) in CAD pts as compared to controls (Table 2). The gene discussed is IL10; the disease is coronary artery disorder.