Various biopsy predictors that were considered are: Patient Age, Primary Gleason Grade, Secondary Gleason Grade, Biopsy Gleason Score, Prostate Specific Antigen (PSA), PSA Density (PSAD), Digital Rectal Exam (DRE), Transrectal Ultrasound (TRUS), Gland Volume, Number of Positive Cores, Total percent of Cores Involvement, and Total Cancer Length in mm. Here, KLK3 is linked to cancer.