EGF and neoplasm: On the basis of our in vitro tumor growth assay data, we conclude that the MSC produced paracrine factors HGF, FGF, TGF-β, VEGF and EGF do not individually affect the growth rate of the Skov-3 xenograft, whereas IL-6 does enhance the proliferation as confirmed by the IP of IL-6 out of MSC conditioned medium (Figure 5B).