CRP and bacterial infectious disease: Based on these observations, we defined a two-step model for the diagnosis of bacterial infection: patients with a CRP of 100 mg/L or higher, or patients with a CRP less than 100 mg/L and a CRPv of 1.08 mg/L/hour or higher, which demonstrated a sensitivity of 88% and a specificity of 70% for the diagnosis of bacterial infection as the origin of fever.