FKBP12.6, PP2A and PPI are reported to be lost from the complex in HF in a paced dog model (Marx et al., 2000; Yano et al., 2000) and in a rabbit model of aortic constriction (Ai et al., 2005) and in human HF (Marx et al., 2000). This evidence concerns the gene FKBP1B and hydrops fetalis.