RYR2 and Arrhythmogenic right ventricular dysplasia: RyR2, purified from an arrhythmogenic right ventricular cardiomyopathy (ARVC) patient heterozygous for G1885E/G1886 and G1885/G1886S, was compared for single channel characteristics to an ARVC patient with a RyR2 WT genotype, but whose heart was removed for transplant for cardiomyopathy (Milting et al., 2006).