On the contrary, IGF-I was significantly lower in emphysematous patients compared to patients with chronic bronchitis both on D1 and D15 [49.5 (40.1–65.4)] versus [70.5 (48.6–78.5)] ng/ml, p = 0.003 on D1 and [84.7 (74.4–96.9)] versus [112.7 (92.4–124.1)] ng/ml, p < 0.001 on D15) (Table 4 and Table 5, Figure 1). Here, IGF1 is linked to chronic bronchitis.