SCD5 and cystic fibrosis: Among the genes showing expression change comparing WT and CF DC upon P. aeruginosa infection, were 3β-hydroxysterol-Δ7 reductase (Dhcr7) and stearoyl-CoA desaturase 2 (Scd2), two enzymes involved in the lipid metabolism that are also regulated by SREBP [33-37].