To identify target genes regulated by the FE65/Teashirt3 complex, lines of H4 cells stably expressing GFP or both FE65 and Teashirt3 were established and analyzed using the Oligo GEArray Human Alzheimer's Disease Microarray, looking for genes that showed reduced expression when both FE65 and Teashirt3 were expressed. The gene discussed is APBB1; the disease is Alzheimer disease.