APBB1 and Cognitive impairment: When gene expression was studied as a function of the degree of cognitive impairment (as measured by CDR), significant difference were seen for FE65 and the Teashirt genes, particularly Teashirt3 (FE65: F6, 89 = 3.160, p = 0.007; Teashirt1: F6, 89 = 2.613, p = 0.022; Teashirt2: F6, 89 = 2.660, p = 0.0020; Teashirt3: F6, 89 = 3.262, p = 0.006).