In these subgroups, there appeared to be better inverse correlation between caspase-4 and FE65 or Teashirt3 levels in controls than in AD, although the smaller numbers of controls reduced the power to identify significant correlations in that group (correlations between caspase-4 and FE65 or Teashirt3 in the control group were r = −0.326, p = 0.064 and r = −0.278, p = 0.117, whereas in the AD group, these values were r = −0.049, p = 0.707 and r = −0.084, p = 0.522). This evidence concerns the gene CASP4 and Alzheimer disease.