CXCL10 and parasitic infectious disease: To that end, P. berghei ANKA infected C57BL/6 wild-type, MHC II−/− and β2-microglobulin−/− mice were injected with anti-IP-10 or isotype control antibodies, and parasitemia levels were determined at different times p.i. Similar to wild-type mice, anti-IP-10-treatment significantly reduced parasitemia in β2-microglobulin−/− mice (Figure 9A).