To determine whether Tregs present during acute malaria infection might similarly affect the induction of immunological memory, we compared FOXP3 mRNA levels on day 0 with malaria specific IFN-γ memory responses (as assessed by PfSE-specific cultured ELISPOT) among PBMC collected from 34 of our convalescent malaria patients (19 severe and 15 uncomplicated) on Day 28. Here, FOXP3 is linked to malaria.